Description
Composition:
Each bolus contains Albendazole USP 600 mg.
Pharmacology:
All benzimidazoles, including albendazole, binds to tubulin, a structural protein of microtubules. These microtubules are important organelles involved in the motility and secretion processes of cells in all living organisms. The blocking of microtubules disturbs the uptake of glucose, which eventually empties the glycogen reserves. This blocks the whole energy management mechanism of the worms that are paralyzed and die or are expelled. Since cell division is also disturbed, worm egg production and development is also blocked, i.e. most of them also have an ovicidal effect. Albendazole also inhibits a helminth-specific fumarate reductase, an enzyme involved in the energy management of the worm cells as well.
Indication:
Alzol is a broad spectrum anthelmintic. It is used against most nematodes and cestodes. Alzol is effective against these gastro-intestinal parasites: Bunostomum, Chabertia, Cooperia, Haemonchus, Nematodirus, Ostertagia, Strongyloides, Dictyocaulus viviparus, Moniezia expansa, Liver flukes and Paramphistomes. It is also effective against different types of worms, lung flukes and lung nematodes.
Dosage & Administration:
| Animal | Types of worm | Dosage |
| Cattle, Buffalo | Roundworms,Tapeworms, Lungworms | 7.5 mg/ Kg body weight(b. wt) |
| Liver Flukes | 10 mg/ Kg body weight(b. wt) | |
| Horses
|
Roundworms, Pinworms | 7.5 mg/ Kg body weight(b. wt) |
| Lungworms | 25 (b.i.d.) for 5 days. | |
| Goat & Sheep | Roundworms,Tapeworms, Lungworms | 5 mg/ Kg body weight(b. wt) |
| Liver Flukes | 7.5 mg/ Kg body weight(b. wt) |
Side effect:
In several cases nausea, vomiting, diarrhea may occur.
Withdrawal period:
Meat: 8-14 days, Milk: 3-5 days.
Packaging:
4X5’s blisters in a box.