Ecal-D3

Calcium & Vitamin D3
Vitamin and Mineral

Ecal-D3

Description

Composition:

Ecal-D3 Tablet: Each tablet contains Calcium Carbonate USP 1250 mg equivalent to 500 mg elemental Calcium & Vitamin D3 200 IU as Cholecalciferol USP.

Pharmacology:

Both calcium and vitamin D3 are endogenously occurring substances within the body. Calcium is actively absorbed into the body and its levels are controlled by various calcium homeostasis mechanisms, one of which vitamin D3 is involved in.

Indication:

As an adjunct to specific therapy for osteoporosis and in situations requiring therapeutic supplementation of malnutrition e.g. in pregnancy and established vitamin D dependent osteomalacia. The prevention and treatment of calcium deficiency/vitamin D deficiency especially in the housebound and institutionalised elderly subjects. Deficiency of the active moieties is indicated by raised levels of PTH, lowered 25-hydroxy vitamin D and raised alkaline phosphatase levels which are associated with increased bone loss.

Dosage & Administration:

Adults, Elderly and children above 12 years of age: Two tablets to be taken twice a day, preferably two tablets each morning and two tablets each evening. Children: Not recommended for children under 12 years.

Contraindications:

Absolute contra-indications are hypercalcaemia resulting myeloma, bone metastases or other malignant bone disease, sarcoidosis, primary hyperparathyroidism and vitamin D overdosage. Severe renal failure. Hypersensitivity to any of the tablet ingredients. Relative contra-indications are osteoporosis due to prolonged immobilisation, renal stones, severe hypercalciuria.

Warning & Precautions:

Patients with mild to moderate renal failure or mild hypercalciuria should be supervised carefully including periodic checks of plasma calcium levels and urinary calcium excretion. In patients with a history of renal stones, urinary calcium excretion should be measured to exclude hypercalciuria.

Side effects:

The use of calcium supplements has rarely given rise to mild gastro-intestinal disturbances such as constipation, flatulence, nausea, gastric pain or diarrhoea. Vitamin D supplements reported as skin rash.

Drug interaction:

There is an increase risk of hypercalcaemia is vitamin D is given with thiazide diuretics, calcium or phosphate. It also interacts with fluoroquinolones, Antacids, Calcitriol, Tetracycline, Doxycycline, Aminocycline or Oxytetracycline etc. So while taking with any of these drugs consultations of the physicians is needed.

Overdose:

The most serious consequence of acute or chronic overdose is hypercalcaemia due to vitamin D toxicity. Symptoms may include nausea, vomiting, polyuria, anorexia, weakness, apathy, thirst and constipation. Chronic overdoses can lead to vascular and organ calcification as a result of hypercalcaemia.

Storage:

Store at a cool and dry place. Protect from light and moisture. Keep out of reach of children. Keep the container tightly closed.

Packing: Ecal-D3 Tablet:

Each plastic container contains 15/30 tablets.