ETHIPLEX-Z®– Vitamin B Complex + Zinc BP & USP

Chemical Name:
B1: Thiamine
B2: Riboflavin 5- Phosphate
B3: Nicotinamide
B6: Pyridoxine
B12: Cyanocobalamin
Zn: Zinc

Description:
Vitamin B-Complex are a class of water-soluble vitamins that play important roles in cell metabolism and synthesis of red blood cells. Vitamin B-Complex is indicated for prophylactic or therapeutic nutritional supplementation in physiologically stressful conditions. Deficiency of vitamin B causes glossitis, stomatitis, polyneuritis, beriberi, pellagra. Zinc is vital for many biological functions such as immunity enhancement, wound healing, digestion, reproduction, physical growth and mental development. Zinc supports normal growth and development during pregnancy, childhood, and adolescence. Zinc also has some antioxidant properties.

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ETHIPLEX-Z®– Vitamin B Complex + Zinc BP & USP

COMPOSITION
ETHIPLEX-Z® is a preparation of Zinc sulphate Monohydrate and vitamin B complex. It is composed of Zinc, Thiamine, Riboflavin, Pyridoxine and Nicotinamide.

PHARMACOLOGY
This syrup is the preparation of Iron, Vitamin B complex and Zinc. In this preparation, Iron is present as Iron (III) Hydroxide Polymaltose Complex. Iron (III) Hydroxide Polymaltose Complex facilitates a controlled absorption of the iron when it comes in contact with the mucosal cell surface. Due to non-ionic nature, this Iron (III) Hydroxide Polymaltose Complex is more stable than conventional Iron form.

INDICATIONS
This syrup is indicated for the treatment and prevention of Zinc & vitamin B deficiencies.

DOSAGE & ADMINISTRATION
SYRUP
Children (Under 10 kg): 1 tablet or 1 teaspoonful (5 ml) daily after meal or as recommended by the registered physician.
Children (10-30 kg): 1 tablet or 1 teaspoonful (5 ml) 3 times daily after meal or as recommended by the registered physician.
Adult and children: 1-2 tablets or 1-2 teaspoonfuls (5-10 ml) 3 times daily after meal or as recommended by the registered physician.

CONTRAINDICATIONS
It is contraindicated in individual known to be hypersensitive to any of active ingredients.

PRECAUTIONS
In actual renal failure zinc accumulation may occur; in that case, dosage adjustment is needed. It is not intended for treatment of severe specific deficiencies.

SIDE EFFECTS
ETHIPLEX-Z® is generally well tolerated. However, a few side effects like nausea, vomiting, diarrhea, stomach upset may occur. Side effects have been reported with specific vitamins but generally at levels substantially higher those available in ETHIPLEX-Z®.
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DRUG INTERACTIONS
Concomitant intake of a tetracycline and Zinc may decrease the absorption of both the tetracycline and zinc. Similarly concomitant administration of Zinc and quinolone may also decrease the absorption of both. Concomitant intake of penicillamine and zinc may depress absorption of Zinc. As little as 5 mg pyridoxine daily can decrease the efficiency of Levadopa in the treatment of Parkinsonism.

PREGNANCY & LACTATION
ETHIPLEX-Z® can be used in pregnancy & lactation.

OVERDOSAGE EFFECTS
Symptoms of overdose may include severe nausea, vomiting, Dizziness, convulsions and coma after apparent recovery. In case of overdose one should seek emergency medical attention

STORAGE CONDITIONS
Store in a cool, dry place & below 30° C. Protected from light. Keep out of reach of children.

PACKING
ETHIPLEX-Z® tablet: Bottle containing 30 tablets each. Each tablet contains Zinc sulphate monohydrate USP equivalent to elemental zinc 10 mg, Thiamine mononitrate USP 5 mg, Riboflavin USP 2 mg, Pyridoxine hydrochloride USP 2 mg, Nicotinamide USP 20 mg

ETHIPLEX-Z® Syrup : Bottle containing 100 ml/200 ml syrup. Each 5 ml syrup contains Zinc sulphate monohydrate USP equivalent to elemental zinc 10 mg, Thiamine mononitrate USP 5 mg, Riboflavin USP 2 mg, Pyridoxine hydrochloride USP 2 mg, Nicotinamide USP 20 mg

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