Etracin® Vet 100 Injection

CHEMICAL NAME:
(4S,4aR,5S,5aR,6S,12aS)-4-(Dimethylamino)-3,5,6,10,11,12a-hexahydroxy-6-methyl-1,12-dioxo-1,4,4a,5,5a,6,12,12a-octahydrotetracene-2-carboxamide

DESCRIPTION:
Oxytetracycline is under group of Tetracycline’s which bind to the 30s ribosomal subunit of bacterial ribosome and interfere with the binding of aminoacyl-tRNA to the mRNA molecule in ribosome complex. Thereby interfering with the bacterial protein synthesis in growing or multiplying of bacteria, leading to bacteriostatic. But higher concentration results in bactericidal action.

—- 10 ml injectable vial in a box
—- 30 ml injectable vial in a box
—- 100 ml injectable vial in a box

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Etracin® Vet 100 Injection
Oxytetracycline BP and Lignocaine BP

COMPOSITION
Each ml injection contains Oxytetracycline BP 100 mg and Lignocaine BP 2%.

MODE OF ACTION
Etracin® Vet 100 Injection prevents cell growth by inhibiting translation. It binds to the 30S ribosomal subunit and prevents the amino-acyl tRNA from binding to the A site of the ribosome. The binding is reversible in nature. Oxytetracycline is lipophilic and can easily pass through the cell membrane or passively diffuses through porin channels into the bacterial membrane.

INDICATION
For the treatment and prevention of different types of bacterial diseases of cattle, buffalo, sheep, goat, deer, rabbit and poultry.
Cattle, Buffaloes, Sheep, Goat & Deer:
For the treatment of Actionabilities, Bacterial Enteritis, Bacterial Pneumonia, Bovine Respiratory Disease Complex, Diphtheria, Keratoconjunctivitis (pink eye), Leptospirosis, Metritis, Anaplasmosis, Foot-rot, Black Leg, Navel ill, Joint ill, Heart Water Disease, Dermatophilosis, Enzootic Abortion (Bedsoniasis), Wound Infections and Mycoplasmas. It also aids in the control or prevention of shipping fever, Pneumonia, post-operative and post-parturient infections.

Rabbit: For the prevention and treatment of conditions / diseases susceptible to Oxytetracycline including infections due to Pasteurella multocida, Bordetella bronchiseptica, Escherichia coli and Salmonella spp. etc.

Poultry: For the prevention and treatment of conditions / diseases susceptible to Oxytetracycline including Fowl Cholera, Fowl Typhoid, complicated CRD etc.

DOSAGE AND ADMINISTRATION
Cattle, Buffaloes, Sheep, Goat & Deer:
Single dose treatment of 1 ml/10 kg body weight. (20 mg/kg b.w.) by intramuscular (I/M) route for 3-5 Days. For anaplasmosis the treatment should be given daily for 28 days.
Poultry & Rabbit:
Single dose treatment of 0.25 ml/kg body weight (50 mg/kg b.w.) by subcutaneous (S/C) route. Severe infections may require re-treatment at 3 to 5 days following initial injection.

Or, as per direction of Registered Veterinarian.

CONTRAINDICATION
Etracin® Vet 100 Injection is contra-indicated to use with drug or food containing calcium

SIDE EFFECT
General toxicity is low although collapse has been reported with tetracycline in weak and debilitated animals.

Although reports of adverse reactions associated with oxytetracycline administration include restlessness, ataxia, trembling, swelling of eyelids, ears, muzzle, anus and vulva (or scrotum and sheath in males), respiratory abnormalities (labored breathing), frothing at the mouth, collapse and possibly death. Some of these reactions may be attributed either to anaphylaxis (an allergic reaction) or to cardiovascular collapse of unknown cause.

USE IN PREGNANCY AND LACTATION
Etracin® Vet 100 Injection should not be used during pregnancy because of the risk of hepatotoxicity in the mother as well as the effects developing in fetus. Use in pregnancy and lactation may result in impaired bone growth and reduce milk production.

WITHDRAWAL PERIOD:
Meat-7 days, Poultry meat-2 days & Eggs-4 days

STORAGE
Store away from light in a cool and dry place.
Keep all medicines out of reach of children.

PACK SIZE
10 ml, 30 ml and 100 ml in injectable vial.

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