Maclid 250 Capsule: Each capsule contains Azithromycin dihydrate USP equivalent to Azithromycin 250 mg.

Maclid 500 Capsule: Each capsule contains Azithromycin dihydrate USP equivalent to Azithromycin 500 mg. Maclid Taste Masked PFS: When reconstituted each 5 ml suspension contains Azithromycin dihydrate USP equivalent to Azithromycin 200 mg.


Maclid (Azithromycin) is indicated for infections caused by susceptible organisms in lower respiratory tract infections including Bronchitis and Pneumonia, skin and soft tissue infections, otitis media and in upper respiratory tract infections including sinusitis, pharyngitis and tonsillitis. Maclid is indicated in the treatment of uncomplicated genital infections due to chlamydia trachomatis.

Dosage & Administration:

Adult: Maclid should be given as 500 mg once daily orally for 3 days or as an alternative, given over 5 days with 500 mg on day 1, then 250 mg on days 2-5. For sexually transmitted diseases caused by chlamydia trachomatis in adults, the dose is 1 gm as a single dose. Normal adult dose is recommended for elderly patient. Children: For children over 6 months recommended dose is 10 mg/kg once daily for 3 days; or if body weight is 15-25 kg: 200 mg once daily for 3 days, body weight is 26-35 kg: 300 mg once daily for 3 days, body weight is 36-45 kg: 400 mg once daily for 3 days. As common with many other antibiotics, Azithro mycin shoud be taken at least 1 hour before of 2 hours after meal and antacid.


Azithromycin is contraindicated in patients hypersensitive to Azithromycin or any other macrolide antibiotic. Co-administration of Ergot derivatives and Azithromycin is contraindicated. Azithromycin is contraindicated in patients with hepatic diseases.

Side Effects:

Azithromycin is well tolerated with a low incidence of side effects. Majority of the side effects are mild to moderate in nature and of gastrointestinal in origin with nausea, abdominal discomfort, vomiting, flatulence and diarrhoea. Allergic reactions such as rash have occurred and there have also been reports of serious hypersensitivity reactions.


As with any antibiotic, observation for signs of super-infection with non-susceptible organisms, including fungi is recommended. No dose adjustment is need in of patients with renal inpairment.

Use in Pregnancy & Lactation:

Animal reproduction studies have demonstrated that Azithromycincrosses the placenta, but have revealed no evidence of harm to the fetus. There are no adequate and well-controlled studies in pregnant women. Since animal reproduction studies are not always predictive of human response, Azithromycin should be used during pregnancy only if adequate alternatives are not available No data on secretion of Azithromycin in breast milk is available, so Azithromycin should only be used in lactating mothers where adequate alternatives are not available.

Drug Interaction:

Azithromycin absorpiton is reduced in presence of food and antacid. So, Azithromycin should be administered 1 hour before or 2 hours after taking food and antacid. in patients receiving Ergot alkaloids Azithromycin should be avoided concur rently because of the possibility of ergotism resulting from interaction of Azithromycin with the cytochrome P-450 system. However, no cases of such interaction have been reported. Macrolide have been known to increase the plasma concentration of digoxin and cyclosporin. Therefore, if co-administration is necessary, caution should be exercised and serum level of digoxin and cyclosporin should be checked. There have been no pharmacokinetic drug interac tions between Azithromycin and Warfarin, theophyline, carbamazepine, methyl-prednisolone and cemitidine.

Over Dosage:

There is no data on over dosage with Azithromycin. Typical symptoms of over dosage with macrolide antibiotics include hearing loss, severe nausea, vomiting and diarrhoea. Gastric lavage and general supportive measures are indicated.


Maclid 250 Capsule: Box contains 1×6’s capsules in Alu-Alu blister strip pack.

Maclid 500 Capsule: Box contains 2×3’s capsules in Alu-Alu blister strip pack.

Maclid Taste Masked PFS: Each bottle contains powder for reconstitution of 15/35 ml suspension.